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Substance Found in Red Wine and Grapes May Slow Aging – Resveratrol Helps Diseases Related to Obesity – Diabetes – Heart Disease

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Substance Found in Red Wine and Grapes May Slow Aging – Resveratrol Helps Diseases Related to Obesity – Diabetes – Heart Disease

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Although research has only been done on mice, researchers say that the substance called resveratrol may extend the lifespan for humans even in people with unhealthy lifestyles. David Sinclair said that “Mice are much closer evolutionarily to humans than any previous model organism treated by this molecule, which offers hope that similar impacts might be seen in humans without negative side-effects.” Sinclair is the Harvard Medical School associate professor of pathology and co-director of the Paul F. Glenn Labs for the Biological Mechanisms of Aging.

Resveratrol increased the lifespan of obese mice. The researchers found that the drug reversed nearly all of the changes in gene expression patterns found in mice on a high calorie diets. These gene expressions are associated with diabetes, heart disease, and other significant diseases related to obesity.

"After six months, resveratrol essentially prevented most of the negative effects of the high calorie diet in mice," said Rafael de Cabo, Ph.D., the study's other co-senior investigator from the National Institute on Aging's Laboratory of Experimental Gerontology, Aging, Metabolism, and Nutrition Unit. "There is a lot of work ahead that will help us better understand resveratrol's roles and the best applications for it."

Although previous research has shown that resveratrol extended the life of worms and flies by nearly 30 percent and fish by almost 60 percent, this is the first study to show that it can extend the life of mammals. It has also been shown to protect against Huntington's disease in two different animal models (worms and mice).

Sinclair says the "healthspan benefits we saw in the obese mice treated with resveratrol, such as increased insulin sensitivity, decreased glucose levels, healthier heart and liver tissues, are positive clinical indicators and may mean we can stave off in humans age-related diseases such as type 2 diabetes, heart disease, and cancer, but only time and more research will tell."

Resveratrol is found in the skins of red grapes and in red wine. The problem is you may need to drink gallons of red wine per day to see any benefit, according to one report by NBC. There are supplements available, but even those may not provide enough of the substance.

Resveratrol is a powerful anti-oxidant which has been reported to keep the skin looking younger as well as protecting the heart and blood vessels. The UK Hairdesser's site says that the younger red wines have more anti-ageing properties than the oak-aged varieties. Comment on this at our Forum

By Dan Wilson
Best Syndication Writer

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